Deodorants and antiperspirants affect the axillary bacterial community - Peeref (2025)

Summary: The pilot study identified a diverse range of Corynebacterium species on human skin, including previously unreported species. The study revealed individual variations in biochemical and resistance profiles among the strains. This highlights the importance of cultivation-based studies in understanding the properties of these microorganisms.

BMC MICROBIOLOGY (2023)

Summary: Infections following cutaneous surgical procedures are rare, and the microbiome of normally healing surgical skin wounds has not been thoroughly studied. This research found that potentially pathogenic bacteria were suppressed in noninfected wounds, while members of the Corynebacterium genus were dominant. This suggests that commensal bacteria on the skin may play a role in reducing infection risk.

MICROBIOLOGY SPECTRUM (2023)

Summary: The skin microbiome is crucial for skin health, and its imbalance is associated with various skin issues. Cosmetic companies are developing products containing prebiotics, probiotics, and other ingredients to maintain the balance of the skin microbiome. In addition, ingestible beauty supplements such as oral probiotics are also attracting attention, highlighting the connection between the gut and skin.

JOURNAL OF MICROBIOLOGY (2024)

Summary: The microorganisms living on human skin have adapted to the challenging conditions that usually hinder microbial growth. They have developed a preference for high concentrations of sweat, while the preference for sebum varies among different bacterial species. These findings provide insights into the composition of skin microbiomes and underscore the importance of studying microorganisms in their natural environment.

MICROBIOLOGY SPECTRUM (2023)

Summary: This study investigated the underlying interactions that maintain the health of the skin microbiome and found that certain skin-associated bacteria can produce cobalamin, which is essential for metabolism. The study also demonstrated that Corynebacterium amycolatum supports the growth of Escherichia coli by producing cobalamin, revealing the phenomenon of metabolite sharing among microorganisms. This finding is significant for understanding the interactions within the microbiome and developing approaches to promote health.

MSPHERE (2024)

Summary: The skin is a diverse ecosystem that houses a variety of microorganisms. This study investigated the variability of the skin microbiome and skin biophysical parameters according to season over the course of one year. The research found that the composition of the skin microbiome fluctuated with the seasons and showed significant associations with skin characteristics, such as skin barrier function.

FRONTIERS IN MICROBIOLOGY (2023)

Summary: This study evaluated the impact of low-pH cosmetic products on the skin microbiome of post-menopausal women. The results showed that the diversity of the natural skin microbiome increased after using the products, and none of them caused significant disruption. Notably, the native algae mask significantly reduced the presence of Corynebacterium and lowered the pH. This suggests that low-pH skincare products may have a positive impact on the diversity and health of the skin microbiome.

DERMATOLOGY AND THERAPY (2024)

Summary: This study shows that a synthetic sandalwood-like odorant can upregulate the expression of the intrafollicular antimicrobial peptide DCD by activating the olfactory receptor OR2AT4, thereby controlling microbial overgrowth. This finding provides a new idea for the treatment of folliculitis and dysbiosis-related hair diseases.

JOURNAL OF DERMATOLOGICAL SCIENCE (2023)

Summary: The vaginal microbiome of healthy women contains nondiphtheria corynebacteria, which may serve as potential probiotics capable of inhibiting the growth of pathogenic microorganisms and supporting colonization resistance in the vaginal biotope.

MICROORGANISMS (2022)

Summary: This article discusses the use of probiotics in cosmetics, including their definition, benefits for skin health, and methods of manipulating the skin microbiome. It also covers the commercial availability and effects of probiotics in cosmetics, as well as the technical challenges and future research directions in this field.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2024)

Summary: In this study, comparative genomics was used to investigate the genetic traits that differentiate a phylogenetically related group of Corynebacterium, the Corynebacterium tuberculostearicum species complex. The study found that different species within the complex are associated with specific body sites and that one species increases in abundance during atopic dermatitis flares.

MICROBIOLOGY SPECTRUM (2023)

Summary: The effects of probiotics and prebiotics on intestinal health have been well studied, and microbiome-targeted solutions are also commercially available. Although people are increasingly aware of the presence of certain microbes on the skin, our understanding of whether the use of skin-resident microbes for beneficial effects has the same potential as the targeted manipulation of the gut microbiota is still limited. Here, we introduce the molecular mechanisms of cross-communication between human skin and the skin microbial community, as well as the impact of these interactions on the host's cutaneous health, which is of great significance for the development of skin cosmetic and therapeutic solutions. Malassezia yeasts, as the main fungal representatives of the skin microbiome, interact with the human host skin through lipid mediators, some of which have strong anti-inflammatory activities. Therefore, this review focuses on Malassezia and provides a comprehensive overview of the current state of knowledge about these fungal-derived lipid mediators and their ability to reduce aesthetic and sensory burdens, such as redness and itching, commonly associated with inflammatory skin conditions. Finally, several examples of current skin microbiome-based interventions for cosmetic solutions are discussed, and models are presented for the use of skin-resident microbes as endogenous bio-manufacturing platforms for the in situ supplementation of the skin with beneficial metabolites.

MICROORGANISMS (2024)

Summary: Skin pigmentation is caused by melanin accumulation, which is produced by melanocytes to protect human skin from harmful ultraviolet radiation. During skin cell renewal, melanin and dead skin cells are removed. However, prolonged exposure to ultraviolet rays or aging can disrupt this cycle, leading to melanin accumulation and skin pigmentation. In the current study, we aim to identify metabolites produced by skin microbiota that inhibit tyrosinase. Specifically, mushroom tyrosinase was used as a model. After screening commensal skin bacteria, Corynebacterium tuberculostearicum was found to inhibit tyrosinase activity. The active compound was cyclo(l-Pro-l-Tyr), and commercially available cyclo(l-Pro-l-Tyr) also showed inhibitory activity. Docking simulations suggested that cyclo(l-Pro-l-Tyr) binds to the substrate-binding site of mushroom tyrosinase, blocking the substrate pocket and preventing its activity. Therefore, cyclo(l-Pro-l-Tyr) may have potential applications as a cosmetic agent and food additive.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2024)

Summary: This study explores the transfer of the skin microbiome onto clothing, its persistence on fabrics, and its transferability between different garments and the environment. It also compares the efficiency of three QIAGEN microbiome extraction kits and checks for human DNA in the extracts. The results show differences in the skin microbiome between volunteers, differences in microbial composition between worn and unworn clothing, the influence of the environment on unworn clothing, the potential use of certain phyla as biomarkers, extraction biases in the kits, and the inability to type human genetic profiles. The study provides additional insights into the potential forensic applications of microbiome analysis on garments.

GENES (2024)

Summary: Probiotics can exert their benefits on the skin, preventing and treating various skin diseases, and aiding wound healing. Scientific reports indicate that specific probiotic strains can modulate cutaneous microflora, skin immune system, lipid barrier, and skin health preservation.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2022)

Summary: This study evaluated the removal of a gaseous mixture containing various hydrocarbons in aerated stirred bioreactors inoculated with Rhodococcus erythropolis under non-sterile conditions. Selected-Ion Flow Tube Mass Spectrometry was used for real-time measurement of hydrocarbons. The effect of the carbon source on bioreactor performance and microbial community evolution was investigated. Results showed that cyclohexane had a high removal efficiency in BR1, and almost complete removal of the most water-soluble and easily degradable carbon sources was observed in BR2, while the removal efficiency of the remaining compounds was low. Exposure to the most recalcitrant hydrocarbons increased the removal efficiency. Additionally, airborne microorganisms populated the bioreactors, and the type of carbon source influenced the microbial community. The abundance of Rhodococcus species was low at the end of the experiments. This work provides fundamental insights into microbial hydrocarbon removal.

JOURNAL OF ENVIRONMENTAL SCIENCES (2025)

Summary: This article discusses the use of probiotics or synbiotics to restore the host-microbiome equilibrium and the evaluation of the efficacy of probiotic candidates. The study found that different probiotic or synbiotic species and strains have different effects on oral pathogens and commensals, as well as anti-inflammatory activities. Therefore, when choosing probiotic strains, a judicious selection based on specific pathologies is required, rather than just based on form or assumptions.

PROBIOTICS AND ANTIMICROBIAL PROTEINS (2024)

Summary: This study presents a method for determining the mechanism of action of new antimicrobial compounds using flow cytometry. The method is cost-effective and fast, and can be predicted through phenotypic fingerprinting and random forest classifiers. The study shows that the method performs well in cultures of Actinomyces viscosus and Fusobacterium nucleatum, and can successfully predict the mechanism of action of cephalothin.

MICROBIOLOGY SPECTRUM (2024)

Summary: This study investigated the addition of (bio)surfactants in biofilters to enhance the removal of cyclohexane and hexane from a polluted gas stream. The results showed that Tween 80 had a positive effect in some cases, while the addition of saponin improved the removal efficiency in all cases, especially in BF3. In addition, the addition of (bio)surfactants led to a shift in the microbial consortia. This study provides recommendations for future studies in this field.

JOURNAL OF ENVIRONMENTAL MANAGEMENT (2024)

Summary: This study investigated the combined impact of plant-growing media composition and bacterial community inoculation on the root-associated bacterial community of hydroponically grown lettuce. The results revealed distinct root-associated bacterial community structures influenced by variations in plant-growing media raw materials, but bacterial community inoculation could independently modulate the root-associated bacterial communities. Bacterial diversity was identified as a key factor in plant growth performance, challenging the notion of hydroponic systems as sterile environments and emphasizing the significance of selecting proper raw materials and bacterial community inoculation for shaping root-associated bacterial communities in controlled environment agriculture to promote plant growth.

MICROBIAL BIOTECHNOLOGY (2024)

Summary: This study investigated the growth characteristics and interactions of lactic acid and chain-elongating bacteria in a granular sludge bioprocess for the production of caproic acid through sugar-based chain elongation metabolism, providing a basis for bioprocess design and optimization.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2024)

Summary: This study investigated the efficacy of six antimicrobial mouth rinses on in vitro oral biofilms under periodontitis-simulating conditions. The results showed that three rinses significantly reduced the abundance of pathobionts, decreased the metabolic activity of the biofilms, and reduced interleukin-8 production in human oral keratinocytes. These mouth rinses may be useful for preventing/delaying disease recurrence in maintenance/supportive periodontal therapy.

JOURNAL OF PERIODONTOLOGY (2024)

Summary: This paper investigated the feasibility of using fly ash-based LWA produced by cold bonding as a bacterial carrier. The results showed that LWA coated with sodium alginate can protect bacteria and prevent leakage, while improving the healing efficiency of mortar, but slightly reducing its mechanical properties.

CONSTRUCTION AND BUILDING MATERIALS (2024)

Summary: This article discusses the development of microbial monitoring methods for ensuring drinking water safety. From historical beer brewing to Robert Koch's gelatin plating method in the 19th century, to modern molecular techniques and sequencing technologies, monitoring methods have evolved. However, current practices still have limitations, and more comprehensive monitoring and innovative technologies are needed to ensure the safety of drinking water.

MICROBIAL BIOTECHNOLOGY (2024)

Summary: This study investigated the use of antiseptics in oral healthcare and the increasing tolerance of bacteria to them. It emphasizes the need for surveillance and the discovery of new antimicrobials. Traditional methods for assessing antimicrobial susceptibility have limitations, so a new method was developed using real-time flow cytometry and membrane permeability staining. This method was used to study the responses of two oral pathobionts to different concentrations of antiseptics, and to quantify the damage rate and identify the most susceptible conditions. Phenotypic subpopulations were also detected. The study shows that real-time flow cytometry can provide information on microbial susceptibility in a short time and differentiate between antiseptics, making it a valuable tool in the discovery of new antimicrobial compounds.

MICROBIOLOGY SPECTRUM (2024)

Summary: This article mainly discusses the issue of microbial monitoring of drinking water. It points out that although humanity has taken various measures to address the problem of microbial water pollution, the current monitoring methods still have uncertainties. The article suggests using modern technologies, such as sequencing technology and artificial intelligence, to improve the accuracy and reliability of monitoring.

MICROBIAL BIOTECHNOLOGY (2024)

Summary: This study investigated the potential of hydrogen-oxidizing bacteria (HOB) to produce biostable drinking water. By culturing a biofilm in a continuous trickling filter supplied with hydrogen gas, the treatment significantly improved biostability and reduced bacterial regrowth and invasion potential. The study also hypothesized that nutrient limitation, particularly phosphorus, was a key factor in achieving biostability.

NPJ CLEAN WATER (2024)

Summary: Organic waste in shrimp ponds forms anaerobic zones, leading to sulfide production, which is harmful to shrimp. Molybdate treatment can inhibit sulfide production, and its effect is related to the concentration. The treatment also affects the composition of the microbial community. In conclusion, molybdate has the potential to reduce sulfide accumulation in shrimp ponds.

PEER COMMUNITY JOURNAL (2024)

Summary: This study focuses on the effects of marine bacteria and endotoxins in sea spray aerosols (SSA) on the human innate immune system. SSA samples were collected in the field and laboratory, and their sodium contents, total bacterial counts, and endotoxin concentrations were analyzed. Human reporter cells were exposed to SSA, and the activation of TLR4, TLR2/6, NF-κB, and IRF was investigated. The results showed that SSA samples differentially activated these receptors and transcription factors, and the immune responses were dose-dependently correlated with the total bacterial counts, endotoxin levels, or both. This study reveals the immunostimulatory potential of SSA and provides a basis for further research on the health implications of SSA exposure.

SCIENCE OF THE TOTAL ENVIRONMENT (2024)

Summary: Amplicon sequencing was used to monitor microbial species in the biofilm on the steel surface in the canal. Temporal and spatial differences in the biofilm microbiota were found, and the corrosion rate of the steel was between 242 and 906 g/m2. Pitting corrosion was exacerbated at a specific location, which was presumed to be related to the activities of iron-oxidizing bacteria and sulfur-reducing bacteria. Indications of microbially induced corrosion were more obvious at sites with appropriate microbial composition.

CORROSION ENGINEERING SCIENCE AND TECHNOLOGY (2024)

Summary: This article discusses the role of MSCs in the wound-healing process, including their immunomodulatory capabilities and multipotency, and their potential to accelerate wound healing. Animal models and clinical trials suggest that MSCs can speed up wound healing by enhancing angiogenesis, modulating inflammation, and promoting fibroblast migration.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2025)

Summary: This study identified 5 plasma proteins that are causally associated with inflammatory skin diseases and 19 candidate genes with high colocalization evidence through proteome-wide Mendelian randomization and colocalization analysis, providing additional possibilities for the discovery of new drug targets for inflammatory skin diseases. These potential drug targets still require more research and rigorous validation in future trials.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: Diabetic foot ulcer is a serious complication of diabetes, and Danggui Sini Decoction can improve its symptoms. This study investigated the therapeutic effect and mechanism of Danggui Sini Decoction on diabetic foot ulcer through in vivo and in vitro experiments. The results showed that Danggui Sini Decoction may promote wound healing by regulating the expression of AGEs/RAGE/TGF-β/Smad2/3.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study investigated the mechanism of action of Tiansha mixture (TM) in treating xerosis. Network pharmacology identified bioactive compounds and potential targets in TM, which were validated in a rat model of xerosis. The results showed that TM could alleviate xerosis damage and reduce inflammatory factors, and its effect may be related to the regulation of these pathways.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study investigated PD-1/PD-L1 inhibitor-induced SCLE. 29 patients were included, and their clinical characteristics, treatment, and outcomes were analyzed. The results showed diverse skin manifestations, abnormal serological markers, and characteristic histological changes. Treatment mainly involved corticosteroids, and the rash could gradually subside. The study emphasizes the importance of recognizing and diagnosing this rare adverse reaction.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study evaluated the efficacy of a combined LED helmet and light-guided microneedle patch in treating AGA. The results showed that both red and green LED treatments significantly increased hair density and diameter, with increasing satisfaction scores over time. There were no significant differences in average satisfaction scores or changes in hair density and diameter between the groups, and no serious adverse events were reported. This combined treatment shows promise, with similar efficacy between red and green wavelengths.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This article mainly discusses the current status of the differentiation grading system for cutaneous squamous cell carcinoma (CSCC). The lack of a standardized and reliable grading system has limited the application of CSCC differentiation in clinical practice. The article reviews the historical CSCC differentiation grading systems and introduces the grading system for non-cutaneous head and neck SCC as a reference. Finally, the article emphasizes the importance of establishing a standardized grading system.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study evaluated the trends and future predictions of the burden of disease in children and adolescents under 14 years old worldwide from 1990 to 2019. The results showed that the incidence, prevalence, and YLDs of AD showed a downward trend, with higher rates in women than in men, the highest incidence rate in Asia, and the largest decrease in the United States. With the emergence of therapeutic drugs, the prevalence and YLDs rate decreased significantly, and the downward trend will continue in the future.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: Chronic idiopathic urticaria is difficult to manage, and its exact cause is unknown, but food allergies may be a factor. This systematic review aimed to determine the prevalence of food allergy in patients with CIU. The study found that approximately 25% of patients with food allergies had CIU, and the prevalence of a family history of atopy was 37.9%. There was a significant risk of angioedema in patients with urticaria. These findings are important for identifying high-risk patients and implementing management.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study reveals the mechanism of ELK4 and CHMP6 in regulating the proliferation and ferroptosis of skin cutaneous melanoma cells. Overexpression of ELK4 or CHMP6 promotes cell proliferation, invasion, and migration, while inhibiting ferroptosis. Knockdown of ELK4 or CHMP6 has the opposite effect. ELK4 promotes CHMP6 transcription by binding to its promoter. This study provides potential therapeutic targets for the treatment of skin cutaneous melanoma.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study recruited healthy women from two different cities in Thailand, measured their skin barrier physiological parameters, and analyzed their skin microbiome profiles. The results showed that air pollution could reduce the diversity of the skin microbiome, disrupt its beneficial correlations with skin barrier physiology, and promote the overgrowth of pathogenic microbiome, resulting in skin barrier dysfunction.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study investigated the serum cardiac troponin I level in patients with pemphigus vulgaris and healthy controls. The mean level in patients was higher than that in controls, but the difference was not significant. Analysis also revealed a significant positive correlation between serum cardiac troponin I level and PDAI score, suggesting a potential link between the severity of PV and cardiac involvement, even without clinical symptoms or risk factors. This emphasizes the importance of cardiac monitoring in these patients.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: The study used AD-MSCs to treat moderate/severe psoriasis, showing it's safe and effective, and can improve the adaptive immune system of patients.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study investigated the effects of CCL5 and CXCL12 secreted by ADSCs on HTS formation. The results showed that CCL5 levels were increased in hADSCs cultured in HTS-conditioned medium, while CXCL12 levels were decreased. Inhibition of CCL5 enhanced the inhibitory effect of hADSCs on HTS fibroblast proliferation, while inhibition of CXCL12 attenuated this effect. In a mouse model, hADSCs alleviated HTS through CCL5 and CXCL12. This study provides a new idea for the treatment of HTS.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2024)

Summary: This study investigated the role of miR-128a-3p in psoriasis. The results showed that miR-128-3p was upregulated in psoriatic patients and IL-22-stimulated HaCaT cells, directly targeting SIRT1 and inhibiting its expression. miR-128-3p promoted cell viability, inhibited apoptosis, and enhanced the inflammatory response, while inhibition of miR-128-3p had the opposite effects. These results suggest that miR-128-3p plays an important role in the progression of psoriasis.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2025)